Death-associated protein 6

DAXX
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4HGA, 2KQS, 2KZS, 2KZU, 4H9N, 4H9O, 4H9P, 4H9Q, 4H9R, 4H9S
Identifiers
Aliases	DAXX, BING2, DAP6, EAP1, death-domain associated protein, death domain associated protein, SMIM40
External IDs	OMIM: 603186; MGI: 1197015; HomoloGene: 1033; GeneCards: DAXX; OMA:DAXX - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	33,323,016 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	34,134,564 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; lymph node; ; appendix; ; spleen; ; ventricular zone; ; stromal cell of endometrium; ; blood; ; left testis; ; left adrenal gland; ; left uterine tube;
	Top expressed in
	spermatocyte; ; spermatid; ; genital tubercle; ; seminiferous tubule; ; granulocyte; ; zygote; ; tail of embryo; ; internal carotid artery; ; secondary oocyte; ; thymus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	heat shock protein binding; protein homodimerization activity; protein N-terminus binding; histone binding; p53 binding; protein kinase activator activity; protein binding; enzyme binding; ubiquitin protein ligase binding; transcription factor binding; androgen receptor binding; protein kinase binding; transcription coactivator activity; transcription corepressor activity; SUMO binding; protein heterodimerization activity;
Cellular component	cytosol; PML body; SWI/SNF superfamily-type complex; chromosome; nucleolus; chromosome, centromeric region; nucleoplasm; nucleus; cytoplasm; nuclear body;
Biological process	androgen receptor signaling pathway; chromatin remodeling; nucleosome assembly; positive regulation of protein phosphorylation; regulation of transcription, DNA-templated; regulation of protein ubiquitination; positive regulation of neuron death; transcription, DNA-templated; viral process; negative regulation of transcription, DNA-templated; extrinsic apoptotic signaling pathway via death domain receptors; positive regulation of protein kinase activity; apoptotic process; cellular response to heat; Unfolded Protein Response; cellular response to cadmium ion; cellular response to copper ion; cellular response to diamide; cellular response to sodium arsenite; chromatin organization; positive regulation of nucleic acid-templated transcription; regulation of apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	1616
	13163
ENSG00000231617; ENSG00000206206; ENSG00000227046; ENSG00000206279; ENSG00000204209;
	ENSG00000229396
	ENSMUSG00000002307
	Q9UER7; Q4VX54
	O35613
	NM_001141969; NM_001141970; NM_001254717; NM_001350
	NM_001199733; NM_007829; NM_001355704
	NP_001135441; NP_001135442; NP_001241646; NP_001341
	NP_001186662; NP_031855; NP_001342633
	Wikidata
View/Edit Human	View/Edit Mouse

Death-associated protein 6 also known as Daxx is a protein that in humans is encoded by the DAXX gene.