DBX2

DBX2
Identifiers
Aliases	DBX2, developing brain homeobox 2
External IDs	MGI: 107445; HomoloGene: 54981; GeneCards: DBX2; OMA:DBX2 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	45,051,099 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	95,553,841 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; substantia nigra; ; Hypothalamus; ; C1 segment; ; Amygdala; ; anterior cingulate cortex; ; prefrontal cortex; ; putamen; ; hippocampus proper;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; lumbar subsegment of spinal cord; ; phalanx of foot; ; hallux; ; visual cortex; ; embryo; ; phalanx of big toe; ; primary visual cortex; ; phalanx of second toe; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	sequence-specific DNA binding; DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	440097
	223843
	ENSG00000185610
	ENSMUSG00000045608
	Q6ZNG2
	n/a
	NM_001004329
	NM_207533
	NP_001004329
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein DBX2, also known as developing brain homeobox protein 2, is a protein that in humans is encoded by the DBX2 gene. DBX2, a homeodomain-containing protein, plays an important role in the development of the central nervous system, specifically in the development of the neural tube and brain. The gene DBX2 is located on chromosome 12 and is approximately 36,000 base pairs long. DBX2 is predicted to enable DNA-binding transcription activity as well as being involved in the regulation of transcription by RNA polymerase II.