DCAF15

DCAF15
Identifiers
Aliases	DCAF15, C19orf72, DDB1 and CUL4 associated factor 15
External IDs	MGI: 2684420; HomoloGene: 18182; GeneCards: DCAF15; OMA:DCAF15 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	13,961,449 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	84,831,397 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; left testis; ; right testis; ; spleen; ; right hemisphere of cerebellum; ; apex of heart; ; blood; ; skin of leg; ; skin of abdomen; ; right uterine tube;
	Top expressed in
	otic vesicle; ; spermatocyte; ; seminiferous tubule; ; otic placode; ; saccule; ; spermatid; ; epiblast; ; yolk sac; ; thymus; ; intestinal villus;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	Cul4-RING E3 ubiquitin ligase complex; protein-containing complex;
Biological process	protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	90379
	212123
	ENSG00000132017; ENSG00000288453
	ENSMUSG00000037103
	Q66K64
	Q6PFH3
	NM_138353
	NM_172502; NM_001357322
	NP_612362
	NP_766090; NP_001344251
	Wikidata
View/Edit Human	View/Edit Mouse

DDB1 and CUL4 associated factor 15 is a protein that in humans is encoded by the DCAF15 gene.

DCAF15 forms a complex with CUL4A or CUL4B that has E3 ubiquitin ligase activity and is responsible for the proteasome degradation of certain proteins.