Artemis (protein)

DCLRE1C
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3W1B, 3W1G, 4HTP
Identifiers
Aliases	DCLRE1C, A-SCID, DCLREC1C, RS-SCID, SCIDA, SNM1C, DNA cross-link repair 1C
External IDs	OMIM: 605988; MGI: 2441769; HomoloGene: 32547; GeneCards: DCLRE1C; OMA:DCLRE1C - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	14,954,432 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	3,465,167 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; tendon of biceps brachii; ; epithelium of nasopharynx; ; sperm; ; nipple; ; pylorus; ; cardia; ; superior surface of tongue; ; endothelial cell; ; amniotic fluid;
	Top expressed in
	granulocyte; ; tail of embryo; ; zygote; ; genital tubercle; ; morula; ; thymus; ; spermatocyte; ; yolk sac; ; blastocyst; ; embryo;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	5'-3' exonuclease activity; 5'-3' exodeoxyribonuclease activity; damaged DNA binding; single-stranded DNA endodeoxyribonuclease activity; protein binding; nuclease activity; endonuclease activity; exonuclease activity; hydrolase activity;
Cellular component	nonhomologous end joining complex; nucleus; nucleoplasm; Golgi apparatus;
Biological process	response to ionizing radiation; DNA recombination; adaptive immune response; interstrand cross-link repair; protection from non-homologous end joining at telomere; immune system process; chromosome organization; cellular response to DNA damage stimulus; V(D)J recombination; B cell differentiation; double-strand break repair via nonhomologous end joining; telomere maintenance; nucleic acid phosphodiester bond hydrolysis; double-strand break repair; DNA repair;
	Sources:Amigo / QuickGO
Orthologs
	64421
	227525
	ENSG00000152457
	ENSMUSG00000026648
	Q96SD1
	Q8K4J0
NM_001033855; NM_001033857; NM_001033858; NM_001289076; NM_001289077;
	NM_001289078; NM_001289079; NM_022487; NM_001350965; NM_001350966; NM_001350967
NM_001110214; NM_146114; NM_175683; NM_001302674; NM_001302684;
	NM_001362903; NM_001362904
NP_001029027; NP_001029029; NP_001029030; NP_001276005; NP_001276006;
	NP_001276007; NP_001276008; NP_071932; NP_001337894; NP_001337895; NP_001337896
NP_001103684; NP_001289603; NP_001289613; NP_666226; NP_783614;
	NP_001349832; NP_001349833
	Wikidata
View/Edit Human	View/Edit Mouse

Artemis is a protein that in humans is encoded by the DCLRE1C (DNA cross-link repair 1C) gene.