DCP1B

DCP1B
Identifiers
Aliases	DCP1B, DCP1, hDcp1b, decapping mRNA 1B
External IDs	OMIM: 609843; MGI: 2442404; HomoloGene: 51881; GeneCards: DCP1B; OMA:DCP1B - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	2,004,535 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	119,221,616 bp
RNA expression pattern
	Top expressed in
	muscle layer of sigmoid colon; ; smooth muscle tissue; ; body of uterus; ; gonad; ; myometrium; ; right adrenal gland; ; right adrenal cortex; ; popliteal artery; ; tibial arteries; ; left adrenal gland;
	Top expressed in
	seminiferous tubule; ; superior cervical ganglion; ; spermatocyte; ; spermatid; ; otolith organ; ; utricle; ; Rostral migratory stream; ; genital tubercle; ; spinal ganglia; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	enzyme regulator activity; enzyme activator activity; protein binding; mRNA binding; hydrolase activity;
Cellular component	P-body; membrane; intracellular membrane-bounded organelle; nucleus; cytoplasm; cytosol;
Biological process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; positive regulation of catalytic activity; deadenylation-independent decapping of nuclear-transcribed mRNA; deadenylation-dependent decapping of nuclear-transcribed mRNA; exonucleolytic catabolism of deadenylated mRNA;
	Sources:Amigo / QuickGO
Orthologs
	196513
	319618
	ENSG00000151065; ENSG00000284850
	ENSMUSG00000041477
	Q8IZD4
	B9EIX0
	NM_152640; NM_001319292
	NM_001033379
	NP_001306221; NP_689853
	NP_001028551
	Wikidata
View/Edit Human	View/Edit Mouse

mRNA-decapping enzyme 1B is a protein that in humans is encoded by the DCP1B gene.

DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002).[supplied by OMIM]