DDB2

DDB2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3EI4, 3I7L, 4E54, 4E5Z
Identifiers
Aliases	DDB2, DDBB, UV-XPE, damage specific DNA binding protein 2
External IDs	OMIM: 600811; MGI: 1355314; HomoloGene: 83; GeneCards: DDB2; OMA:DDB2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	47,239,217 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	91,067,327 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; skin of leg; ; right uterine tube; ; right adrenal cortex; ; Descending thoracic aorta; ; olfactory zone of nasal mucosa; ; granulocyte; ; left adrenal gland; ; ascending aorta; ; left adrenal cortex;
	Top expressed in
	Paneth cell; ; secondary oocyte; ; zygote; ; medullary collecting duct; ; primary oocyte; ; ascending aorta; ; saccule; ; aortic valve; ; otic vesicle; ; ciliary body;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; ubiquitin-protein transferase activity; protein binding; damaged DNA binding; protein-containing complex binding;
Cellular component	nucleoplasm; cell junction; Cul4B-RING E3 ubiquitin ligase complex; nucleus; Cul4-RING E3 ubiquitin ligase complex; protein-containing complex;
Biological process	nucleotide-excision repair; pyrimidine dimer repair; nucleotide-excision repair, DNA damage recognition; histone H2A monoubiquitination; protein polyubiquitination; cellular response to DNA damage stimulus; global genome nucleotide-excision repair; protein ubiquitination; nucleotide-excision repair, DNA incision; UV-damage excision repair; response to UV; DNA repair; protein autoubiquitination; nucleotide-excision repair, DNA incision, 5'-to lesion; nucleotide-excision repair, preincision complex stabilization; nucleotide-excision repair, preincision complex assembly; protein deubiquitination; post-translational protein modification; response to UV-B; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA incision, 3'-to lesion;
	Sources:Amigo / QuickGO
Orthologs
	1643
	107986
	ENSG00000134574
	ENSMUSG00000002109
	Q92466
	Q99J79
	NM_000107; NM_001300734
	NM_028119; NM_001362705
	NP_000098; NP_001287663
	NP_082395; NP_001349634
	Wikidata
View/Edit Human	View/Edit Mouse

DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene.