DDIT4

DDIT4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3LQ9
Identifiers
Aliases	DDIT4, Dig2, REDD-1, REDD1, DNA damage inducible transcript 4
External IDs	OMIM: 607729; MGI: 1921997; HomoloGene: 10400; GeneCards: DDIT4; OMA:DDIT4 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	72,276,036 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	59,787,656 bp
RNA expression pattern
	Top expressed in
	pericardium; ; right ovary; ; vena cava; ; left ovary; ; tibial nerve; ; mucosa of pharynx; ; olfactory zone of nasal mucosa; ; vagina; ; body of pancreas; ; trachea;
	Top expressed in
	aortic valve; ; muscle of thigh; ; cumulus cell; ; ascending aorta; ; Ileal epithelium; ; neural layer of retina; ; stroma of bone marrow; ; medial ganglionic eminence; ; calvaria; ; secondary oocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	14-3-3 protein binding;
Cellular component	cytoplasm; mitochondrion; intracellular anatomical structure; cytosol;
Biological process	response to hypoxia; negative regulation of peptidyl-threonine phosphorylation; negative regulation of glycolytic process; neurotrophin TRK receptor signaling pathway; negative regulation of intracellular signal transduction; positive regulation of neuron death; brain development; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; apoptotic process; reactive oxygen species metabolic process; cell population proliferation; neuron differentiation; negative regulation of peptidyl-serine phosphorylation; neuron migration; negative regulation of signal transduction; negative regulation of TOR signaling; cellular response to dexamethasone stimulus; defense response to virus; protein-containing complex disassembly; regulation of TOR signaling;
	Sources:Amigo / QuickGO
Orthologs
	54541
	74747
	ENSG00000168209
	ENSMUSG00000020108
	Q9NX09
	Q9D3F7
	NM_019058
	NM_029083
	NP_061931
	NP_083359
	Wikidata
View/Edit Human	View/Edit Mouse

DNA-damage-inducible transcript 4 (DDIT4) protein also known as protein regulated in development and DNA damage response 1 (REDD1) is a protein that in humans is encoded by the DDIT4 gene.