DDX1

DDX1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4XW3
Identifiers
Aliases	DDX1, DBP-RB, UKVH5d, DEAD/H-box helicase 1, DEAD-box helicase 1
External IDs	OMIM: 601257; MGI: 2144727; HomoloGene: 3627; GeneCards: DDX1; OMA:DDX1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	15,634,346 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	13,299,214 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of biceps brachii; ; right ventricle; ; deltoid muscle; ; triceps brachii muscle; ; middle temporal gyrus; ; tendon of biceps brachii; ; parotid gland; ; glutes; ; Skeletal muscle tissue of rectus abdominis; ; islet of Langerhans;
	Top expressed in
	primitive streak; ; spermatid; ; spermatocyte; ; ventricular zone; ; epiblast; ; maxillary prominence; ; mandibular prominence; ; dentate gyrus of hippocampal formation granule cell; ; triceps brachii muscle; ; temporal muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA helicase activity; DNA binding; nucleotide binding; helicase activity; poly(A) binding; chromatin binding; transcription coregulator activity; DNA/RNA helicase activity; protein binding; nucleic acid binding; nuclease activity; double-stranded RNA binding; exonuclease activity; hydrolase activity; ATP binding; RNA binding;
Cellular component	cytoplasm; membrane; nucleoplasm; tRNA-splicing ligase complex; cytoplasmic stress granule; cleavage body; nucleus; cytosol; nucleolus; mitochondrion; ribonucleoprotein complex;
Biological process	regulation of transcription, DNA-templated; response to exogenous dsRNA; mRNA processing; response to virus; protein localization to cytoplasmic stress granule; transcription, DNA-templated; multicellular organism development; spliceosomal complex assembly; DNA duplex unwinding; double-strand break repair; RNA secondary structure unwinding; regulation of translational initiation; tRNA splicing, via endonucleolytic cleavage and ligation; tRNA processing; nucleic acid phosphodiester bond hydrolysis; immune system process; positive regulation of myeloid dendritic cell cytokine production; positive regulation of I-kappaB kinase/NF-kappaB signaling; innate immune response; defense response to virus; regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	1653
	104721
	ENSG00000079785
	ENSMUSG00000037149
	Q92499
	Q91VR5
	NM_004939
	NM_134040
	NP_004930
	NP_598801
	Wikidata
View/Edit Human	View/Edit Mouse

ATP-dependent RNA helicase DDX1 is an enzyme that in humans is encoded by the DDX1 gene.