DGAT1

DGAT1
Identifiers
Aliases	DGAT1, ARAT, ARGP1, DGAT, DIAR7, diacylglycerol O-acyltransferase 1
External IDs	OMIM: 604900; MGI: 1333825; HomoloGene: 7688; GeneCards: DGAT1; OMA:DGAT1 - orthologs
EC number	2.3.1.76
Gene location (Human)
Chr.	Chromosome 8 (human)
End	144,326,910 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	76,396,153 bp
RNA expression pattern
	Top expressed in
	duodenum; ; mucosa of transverse colon; ; right adrenal cortex; ; left adrenal cortex; ; left testis; ; right testis; ; apex of heart; ; right lobe of liver; ; subcutaneous adipose tissue; ; blood;
	Top expressed in
	granulocyte; ; duodenum; ; crypt of lieberkuhn of small intestine; ; jejunum; ; brown adipose tissue; ; ileum; ; intestinal villus; ; epithelium of small intestine; ; tunica adventitia of aorta; ; spermatocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; O-acyltransferase activity; protein binding; 2-acylglycerol O-acyltransferase activity; retinol O-fatty-acyltransferase activity; acyltransferase activity; diacylglycerol O-acyltransferase activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; intracellular membrane-bounded organelle; endoplasmic reticulum; plasma membrane; specific granule membrane;
Biological process	glycerolipid metabolic process; retinol metabolic process; lipid storage; fatty acid homeostasis; diacylglycerol metabolic process; triglyceride biosynthetic process; very-low-density lipoprotein particle assembly; long-chain fatty-acyl-CoA metabolic process; triglyceride metabolic process; acylglycerol acyl-chain remodeling; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	8694
	13350
	ENSG00000185000; ENSG00000285482
	ENSMUSG00000022555
	O75907
	Q9Z2A7
	NM_012079
	NM_010046
	NP_036211
	NP_034176
	Wikidata
View/Edit Human	View/Edit Mouse

Diacylglycerol O-acyltransferase 1 is an enzyme that in humans is encoded by the DGAT1 gene.