DHRS4

DHRS4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3O4R
Identifiers
Aliases	DHRS4, CR, NRDR, PHCR, PSCD, SCAD-SRL, SDR-SRL, SDR25C1, SDR25C2, dehydrogenase/reductase (SDR family) member 4, dehydrogenase/reductase 4
External IDs	OMIM: 611596; MGI: 90169; HomoloGene: 49646; GeneCards: DHRS4; OMA:DHRS4 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	23,969,279 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	55,727,797 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; duodenum; ; human kidney; ; mucosa of transverse colon; ; monocyte; ; apex of heart; ; left adrenal cortex; ; left ventricle; ; gastrocnemius muscle; ; right adrenal cortex;
	Top expressed in
	right kidney; ; human kidney; ; proximal tubule; ; left lobe of liver; ; duodenum; ; gallbladder; ; submandibular gland; ; brown adipose tissue; ; Paneth cell; ; saccule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; alcohol dehydrogenase [NAD(P)+ activity]; signaling receptor binding; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; carbonyl reductase (NADPH) activity; 3-keto sterol reductase activity; NADP-retinol dehydrogenase activity;
Cellular component	peroxisomal membrane; peroxisome; extracellular exosome; endoplasmic reticulum membrane; mitochondrion; nucleus; peroxisomal matrix; cytosol;
Biological process	steroid metabolic process; alcohol metabolic process; protein tetramerization; cellular ketone metabolic process; retinol metabolic process; protein targeting to peroxisome;
	Sources:Amigo / QuickGO
Orthologs
	10901
	28200
	ENSG00000157326; ENSG00000284807
	ENSMUSG00000022210
	Q9BTZ2
	Q99LB2
NM_001282987; NM_001282988; NM_001282989; NM_001282990; NM_001282991;
	NM_021004
	NM_001037938; NM_030686
NP_001269916; NP_001269917; NP_001269918; NP_001269919; NP_001269920;
	NP_066284
	NP_001033027; NP_109611
	Wikidata
View/Edit Human	View/Edit Mouse

Dehydrogenase/reductase SDR family member 4 is an enzyme that in humans is encoded by the DHRS4 gene.