DHX15

DHX15
Identifiers
Aliases	DHX15, DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p, DEAH-box helicase 15, hPrp43
External IDs	OMIM: 603403; MGI: 1099786; HomoloGene: 1040; GeneCards: DHX15; OMA:DHX15 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	24,584,554 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	52,347,856 bp
RNA expression pattern
	Top expressed in
	cartilage tissue; ; tibia; ; germinal epithelium; ; mucosa of sigmoid colon; ; visceral pleura; ; skin of hip; ; parietal pleura; ; embryo; ; ventricular zone; ; skin of thigh;
	Top expressed in
	primitive streak; ; Gonadal ridge; ; mandibular prominence; ; maxillary prominence; ; abdominal wall; ; hair follicle; ; medial ganglionic eminence; ; cumulus cell; ; human fetus; ; somite;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	RNA helicase activity; nucleotide binding; double-stranded RNA binding; protein binding; ATP binding; helicase activity; hydrolase activity; nucleic acid binding; RNA binding; 3'-5' RNA helicase activity;
Cellular component	U12-type spliceosomal complex; nucleolus; U2-type post-mRNA release spliceosomal complex; cytoplasm; nucleus; nucleoplasm; nuclear speck;
Biological process	mRNA processing; response to alkaloid; response to toxic substance; RNA splicing; mRNA splicing, via spliceosome;
	Sources:Amigo / QuickGO
Orthologs
	1665
	13204
	ENSG00000109606
	ENSMUSG00000029169
	O43143
	O35286
	NM_001358
	NM_001042620; NM_007839
	NP_001349
	NP_001036085; NP_031865
	Wikidata
View/Edit Human	View/Edit Mouse

Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 is an enzyme that in humans is encoded by the DHX15 gene.

The protein encoded by this gene is a putative ATP-dependent RNA helicase implicated in pre-mRNA splicing. It may have tumor suppressor activity.