DIXDC1

DIXDC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3PZ7
Identifiers
Aliases	DIXDC1, CCD1, DIX domain containing 1
External IDs	OMIM: 610493; MGI: 2679721; HomoloGene: 82369; GeneCards: DIXDC1; OMA:DIXDC1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	112,022,653 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	50,650,817 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; inferior ganglion of vagus nerve; ; corpus callosum; ; urethra; ; saphenous vein; ; superficial temporal artery; ; subthalamic nucleus; ; ventral tegmental area; ; synovial joint; ; mucosa of paranasal sinus;
	Top expressed in
	lobe of cerebellum; ; cerebellar vermis; ; habenula; ; superior colliculus; ; pontine nuclei; ; epithelium of lens; ; dorsomedial hypothalamic nucleus; ; ventral tegmental area; ; neural layer of retina; ; medial dorsal nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	actin binding; gamma-tubulin binding; protein binding; protein domain specific binding;
Cellular component	cytosol; cell junction; focal adhesion; cytoplasm; cytoskeleton;
Biological process	positive regulation of canonical Wnt signaling pathway; multicellular organism development; positive regulation of Wnt signaling pathway; regulation of microtubule cytoskeleton organization; forebrain ventricular zone progenitor cell division; cerebral cortex radially oriented cell migration; cerebral cortex cell migration; regulation of actin cytoskeleton organization; negative regulation of neuron differentiation; Wnt signaling pathway; cell proliferation in forebrain; canonical Wnt signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	85458
	330938
	ENSG00000150764
	ENSMUSG00000032064
	Q155Q3
	Q80Y83
	NM_001037954; NM_001278542; NM_033425
	NM_178118; NM_001311069; NM_001374656
	NP_001033043; NP_001265471; NP_219493
	NP_001297998; NP_835219; NP_001361585
	Wikidata
View/Edit Human	View/Edit Mouse

Dixin is a protein that in humans is encoded by the DIXDC1 gene. When active it stops cancer metastasis due to extreme stickiness, both in vitro and in vivo.