DLG5

DLG5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UIT
Identifiers
Aliases	DLG5, LP-DLG, P-PDLG, discs large homolog 5, discs large MAGUK scaffold protein 5
External IDs	OMIM: 604090; MGI: 1918478; HomoloGene: 3486; GeneCards: DLG5; OMA:DLG5 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	77,926,755 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	24,295,988 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; left adrenal cortex; ; right adrenal cortex; ; ganglionic eminence; ; placenta; ; stromal cell of endometrium; ; pituitary gland; ; skin of abdomen; ; prostate; ; skin of leg;
	Top expressed in
	genital tubercle; ; ventricular zone; ; Gonadal ridge; ; external carotid artery; ; gastrula; ; cumulus cell; ; mandibular prominence; ; stroma of bone marrow; ; tail of embryo; ; human fetus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	beta-catenin binding; cytoskeletal protein binding; protein binding; signaling receptor complex adaptor activity;
Cellular component	membrane; plasma membrane; cell junction; postsynaptic density; ciliary basal body; cytoplasm; cytoskeleton; cell projection; synapse; postsynaptic membrane;
Biological process	regulation of apoptotic process; polarized epithelial cell differentiation; intracellular signal transduction; apical protein localization; establishment or maintenance of epithelial cell apical/basal polarity; protein localization to adherens junction; metanephric collecting duct development; epithelial tube branching involved in lung morphogenesis; zonula adherens assembly; midbrain development; signal transduction; negative regulation of cell population proliferation; epithelial to mesenchymal transition; maintenance of cell polarity; negative regulation of cell migration; negative regulation of hippo signaling; positive regulation of hippo signaling; negative regulation of T cell proliferation; positive regulation of smoothened signaling pathway; positive regulation of synapse assembly; positive regulation of dendritic spine development; cell-cell adhesion; protein-containing complex assembly;
	Sources:Amigo / QuickGO
Orthologs
	9231
	71228
	ENSG00000151208; ENSG00000274429
	ENSMUSG00000021782
	Q8TDM6
	E9Q9R9
	NM_004747
	NM_001163513; NM_027726
	NP_004738
	NP_001156985; NP_082002
	Wikidata
View/Edit Human	View/Edit Mouse

Disks large homolog 5 is a protein that in humans is encoded by the DLG5 gene.