DLL3

DLL3
Identifiers
Aliases	DLL3, SCDO1, pu, pudgy, delta like canonical Notch ligand 3
External IDs	OMIM: 602768; MGI: 1096877; HomoloGene: 7291; GeneCards: DLL3; OMA:DLL3 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	39,508,481 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	28,001,663 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; gonad; ; testicle; ; ventricular zone; ; nucleus accumbens; ; Amygdala; ; anterior cingulate cortex; ; prefrontal cortex; ; Hypothalamus; ; putamen;
	Top expressed in
	medial ganglionic eminence; ; seminiferous tubule; ; tail of embryo; ; primitive streak; ; embryo; ; embryo; ; epiblast; ; spermatid; ; morula; ; pars intermedia;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	Notch binding; calcium ion binding;
Cellular component	integral component of membrane; membrane; plasma membrane;
Biological process	Notch signaling pathway; somitogenesis; multicellular organism development; negative regulation of neurogenesis; cell differentiation; compartment pattern specification; paraxial mesoderm development; tissue development; skeletal system development;
	Sources:Amigo / QuickGO
Orthologs
	10683
	13389
	ENSG00000090932
	ENSMUSG00000003436
	Q9NYJ7
	O88516
	NM_016941; NM_203486
	NM_007866
	NP_058637; NP_982353
	NP_031892
	Wikidata
View/Edit Human	View/Edit Mouse

Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene. Two transcript variants encoding distinct isoforms have been identified for this gene.