DLX1

DLX1
Identifiers
Aliases	DLX1, Dlx, Dlx-1, distal-less homeobox 1
External IDs	OMIM: 600029; MGI: 94901; HomoloGene: 22558; GeneCards: DLX1; OMA:DLX1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	172,089,677 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	71,364,325 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; testicle; ; anterior cingulate cortex; ; endothelial cell; ; ganglionic eminence; ; prefrontal cortex; ; Brodmann area 23; ; dorsolateral prefrontal cortex; ; primary visual cortex; ; Brodmann area 9;
	Top expressed in
	medial ganglionic eminence; ; olfactory bulb; ; nasolacrimal duct; ; Rostral migratory stream; ; otic vesicle; ; otic placode; ; lateral septal nucleus; ; fossa; ; paraventricular nucleus of hypothalamus; ; maxillary prominence;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; chromatin binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity;
Cellular component	nucleus;
Biological process	negative regulation of neuron apoptotic process; cerebral cortex GABAergic interneuron differentiation; proximal/distal pattern formation; cell differentiation; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; embryonic skeletal system development; multicellular organism development; odontogenesis of dentin-containing tooth; cerebral cortex GABAergic interneuron fate commitment; negative regulation of oligodendrocyte differentiation; forebrain neuron differentiation; hippocampus development; subpallium development; negative regulation of Notch signaling pathway; positive regulation of cell differentiation; negative regulation of photoreceptor cell differentiation; positive regulation of amacrine cell differentiation; negative regulation of transcription by RNA polymerase II; negative regulation of BMP signaling pathway; positive regulation of transcription by RNA polymerase II; cellular response to transforming growth factor beta stimulus; cellular response to BMP stimulus; negative regulation of cellular response to transforming growth factor beta stimulus; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	1745
	13390
	ENSG00000144355
	ENSMUSG00000041911
	P56177
	Q64317
	NM_001038493; NM_178120
	NM_010053
	NP_001033582; NP_835221
	NP_034183
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein DLX-1 is a protein that in humans is encoded by the DLX1 gene.