DNAH11

DNAH11
Identifiers
Aliases	DNAH11, CILD7, DNAHBL, DNAHC11, DNHBL, DPL11, dynein axonemal heavy chain 11
External IDs	OMIM: 603339; MGI: 1100864; HomoloGene: 2801; GeneCards: DNAH11; OMA:DNAH11 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	21,901,839 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	118,162,778 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; bronchial epithelial cell; ; mucosa of paranasal sinus; ; right adrenal cortex; ; olfactory zone of nasal mucosa; ; caput epididymis; ; left adrenal gland; ; testicle; ; left adrenal cortex; ; gonad;
	Top expressed in
	zygote; ; secondary oocyte; ; parotid gland; ; utricle; ; primary oocyte; ; cumulus cell; ; olfactory epithelium; ; Epithelium of choroid plexus; ; lens; ; vestibular sensory epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ATP binding; cytoskeletal motor activity; nucleotide binding; microtubule motor activity; ATPase activity; minus-end-directed microtubule motor activity; dynein light chain binding; dynein intermediate chain binding; dynein light intermediate chain binding;
Cellular component	cell projection; cytoplasm; microtubule; cilium; cytoskeleton; dynein complex; motile cilium; axoneme; 9+0 motile cilium; 9+2 motile cilium; proximal portion of axoneme; extracellular region;
Biological process	regulation of cilium beat frequency; microtubule-based movement; cilium movement; flagellated sperm motility; determination of left/right symmetry; heart development; epithelial cilium movement involved in extracellular fluid movement; learning or memory; determination of left/right asymmetry in nervous system; epithelial cilium movement involved in determination of left/right asymmetry; cardiac septum development; cardiac septum morphogenesis; determination of heart left/right asymmetry;
	Sources:Amigo / QuickGO
Orthologs
	8701
	13411
	ENSG00000105877
	ENSMUSG00000018581
	Q96DT5
	n/a
	NM_001277115
	NM_010060
	NP_001264044
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Dynein axonemal heavy chain 11 (DNAH11) is a protein that is encoded by the DNAH11 gene in humans. In mice, the protein is encoded by the Dnahc11 gene, the murine homolog to human DNAH11. The protein was previously known as 'left-right' dynein (with the corresponding gene alias lrd) in mice and is particularly notable during embryogenesis for orientation of the eventual body plan.