DNMT3L

DNMT3L
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2PV0, 2PVC, 2QRV, 4U7P, 4U7T
Identifiers
Aliases	DNMT3L, DNA methyltransferase 3 like
External IDs	OMIM: 606588; MGI: 1859287; HomoloGene: 8362; GeneCards: DNMT3L; OMA:DNMT3L - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	44,262,216 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	77,899,456 bp
RNA expression pattern
	Top expressed in
	testicle; ; liver; ; right lobe of liver; ; human kidney; ; gonad; ; lymph node; ; renal cortex; ; granulocyte; ; tonsil; ; mucosa of transverse colon;
	Top expressed in
	transitional epithelium of urinary bladder; ; primary oocyte; ; blastocyst; ; zygote; ; morula; ; secondary oocyte; ; Gonadal ridge; ; spermatid; ; embryo; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	enzyme binding; enzyme regulator activity; enzyme activator activity; protein binding; metal ion binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytosol; nucleus; ESC/E(Z) complex;
Biological process	regulation of gene expression by genetic imprinting; DNA methylation; regulation of catalytic activity; negative regulation of transcription, DNA-templated; positive regulation of catalytic activity; male meiosis I; spermatogenesis; cell differentiation; DNA methylation on cytosine; DNA methylation involved in gamete generation; stem cell differentiation; negative regulation of DNA methylation; positive regulation of DNA methylation; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	29947
	54427
	ENSG00000142182
	ENSMUSG00000000730
	Q9UJW3
	Q9CWR8
	NM_013369; NM_175867
NM_001081695; NM_001284197; NM_001284198; NM_001284199; NM_001284200;
	NM_019448
	NP_037501; NP_787063
NP_001075164; NP_001271126; NP_001271127; NP_001271128; NP_001271129;
	NP_062321
	Wikidata
View/Edit Human	View/Edit Mouse

DNA (cytosine-5)-methyltransferase 3-like is an enzyme that in humans is encoded by the DNMT3L gene.