Dipeptidase 3

DPEP3
Identifiers
Aliases	DPEP3, MBD3, dipeptidase 3
External IDs	OMIM: 609926; MGI: 1919104; HomoloGene: 23357; GeneCards: DPEP3; OMA:DPEP3 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	67,980,549 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	106,706,061 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; gonad; ; testicle; ; sperm; ; blood; ; granulocyte; ; spleen; ; bone marrow; ; muscle of thigh;
	Top expressed in
	spermatocyte; ; spermatid; ; seminiferous tubule; ; primary oocyte; ; morula; ; morula; ; secondary oocyte; ; blastocyst; ; Gonadal ridge; ; zygote;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptidase activity; metalloexopeptidase activity; dipeptidyl-peptidase activity; metallopeptidase activity; hydrolase activity; metal ion binding; dipeptidase activity;
Cellular component	anchored component of membrane; membrane; acrosomal vesicle; plasma membrane;
Biological process	male meiotic nuclear division; meiosis; proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	64180
	71854
	ENSG00000141096
	ENSMUSG00000031898
	Q9H4B8
	Q9DA79
	NM_022357; NM_001129758; NM_001370198
	NM_027960
	NP_001123230; NP_001357127
	NP_082236
	Wikidata
View/Edit Human	View/Edit Mouse

Dipeptidase 3 (DPEP3) is a protein that in humans is encoded by the DPEP3 gene.

This gene encodes a membrane-bound glycoprotein from the family of dipeptidases (EC 3.4.13.19) involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family, DPEP2. Alternatively spliced transcript variants that encode different isoforms have been found for this gene.