Desmoglein-3

DSG3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5EQX
Identifiers
Aliases	DSG3, CDHF6, PVA, desmoglein 3, ABOLM
External IDs	OMIM: 169615; MGI: 99499; HomoloGene: 55513; GeneCards: DSG3; OMA:DSG3 - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	31,478,702 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	20,680,516 bp
RNA expression pattern
	Top expressed in
	gums; ; gingival epithelium; ; mucosa of pharynx; ; oral cavity; ; body of tongue; ; human penis; ; vulva; ; cervix epithelium; ; skin of thigh; ; skin of abdomen;
	Top expressed in
	esophagus; ; skin of external ear; ; conjunctival fornix; ; cornea; ; lip; ; skin of back; ; skin of abdomen; ; hair follicle; ; lumbar spinal ganglion; ; hand;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; metal ion binding;
Cellular component	integral component of membrane; cytosol; cell junction; desmosome; extracellular exosome; membrane; plasma membrane; cornified envelope; cell-cell junction;
Biological process	cell adhesion; homophilic cell adhesion via plasma membrane adhesion molecules; keratinization; cornification; cell-cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	1830
	13512
	ENSG00000134757
	ENSMUSG00000056632
	P32926
	O35902
	NM_001944
	NM_030596
	NP_001935
	NP_085099
	Wikidata
View/Edit Human	View/Edit Mouse

Desmoglein-3 is a protein that in humans is encoded by the DSG3 gene. In the skin epidermis Desmoglein-3 is expressed in the basal lower layers of the epidermis, and dominates in terms of expression on mucosal surfaces compared to Desmoglein-1.