DTX2

DTX2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1V87
Identifiers
Aliases	DTX2, RNF58, deltex 2, E3 ubiquitin ligase, deltex E3 ubiquitin ligase 2
External IDs	OMIM: 613141; MGI: 1921448; HomoloGene: 56904; GeneCards: DTX2; OMA:DTX2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	76,505,995 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	136,061,726 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; olfactory zone of nasal mucosa; ; sural nerve; ; right testis; ; minor salivary glands; ; left testis; ; blood; ; skin of leg; ; skin of abdomen; ; vagina;
	Top expressed in
	secondary oocyte; ; primary oocyte; ; zygote; ; Rostral migratory stream; ; condyle; ; internal carotid artery; ; fossa; ; external carotid artery; ; hair follicle; ; motor neuron;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; protein binding; metal ion binding; transferase activity;
Cellular component	cytoplasm; nuclear membrane; nucleus; nucleoplasm;
Biological process	Notch signaling pathway; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	113878
	74198
	ENSG00000282379; ENSG00000091073
	ENSMUSG00000004947
	Q86UW9
	Q8R3P2
	NM_001102594; NM_001102595; NM_001102596; NM_020892
	NM_001256096; NM_001256097; NM_001256098; NM_023742
	NP_001096064; NP_001096065; NP_001096066; NP_065943
	NP_001243025; NP_001243026; NP_001243027; NP_076231
	Wikidata
View/Edit Human	View/Edit Mouse

Protein deltex-2 also known as E3 ubiquitin-protein ligase DTX2 is an enzyme that in humans is encoded by the DTX2 gene.

DTX2 functions as a ubiquitin E3 ligase in conjunction with the E2 enzyme UBCH5A.