DUSP15

DUSP15
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1YZ4
Identifiers
Aliases	DUSP15, VHY, C20orf57, dual specificity phosphatase 15
External IDs	OMIM: 616776; MGI: 1934928; HomoloGene: 33586; GeneCards: DUSP15; OMA:DUSP15 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	31,870,664 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	152,793,618 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; tibial nerve; ; human kidney; ; sperm; ; testicle; ; C1 segment; ; Descending thoracic aorta; ; right coronary artery; ; vena cava;
	Top expressed in
	sciatic nerve; ; spermatocyte; ; spermatid; ; seminiferous tubule; ; deep cerebellar nuclei; ; pontine nuclei; ; epithelium of lens; ; cerebellar cortex; ; anterior horn of spinal cord; ; medial vestibular nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	phosphoprotein phosphatase activity; hydrolase activity; protein binding; phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity;
Cellular component	membrane; cytoplasm; cytosol; plasma membrane;
Biological process	positive regulation of JNK cascade; transforming growth factor beta receptor signaling pathway; protein dephosphorylation; regulation of cell population proliferation; peptidyl-tyrosine dephosphorylation; dephosphorylation; regulation of oligodendrocyte differentiation;
	Sources:Amigo / QuickGO
Orthologs
	128853
	252864
	ENSG00000149599
	ENSMUSG00000042662
	Q9H1R2
	Q8R4V2
	NM_177991; NM_001012644; NM_080611; NM_001320478; NM_001320479
	NM_001159376; NM_145744
	NP_001012662; NP_001307407; NP_001307408; NP_542178; NP_817130
	NP_001152848; NP_665687
	Wikidata
View/Edit Human	View/Edit Mouse

Dual specificity protein phosphatase 15 is an enzyme that in humans is encoded by the DUSP15 gene.

The protein encoded by this gene belongs to the non-receptor class of the protein-tyrosine phosphatase family. The encoded protein has both protein-tyrosine phosphatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. Three transcript variants, encoding two different isoforms have been found for this gene.