DUSP4

DUSP4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3EZZ
Identifiers
Aliases	DUSP4, HVH2, MKP-2, MKP2, TYP, dual specificity phosphatase 4
External IDs	OMIM: 602747; MGI: 2442191; HomoloGene: 1065; GeneCards: DUSP4; OMA:DUSP4 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	29,350,684 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	35,287,048 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; buccal mucosa cell; ; lactiferous duct; ; seminal vesicula; ; palpebral conjunctiva; ; sperm; ; trachea; ; mucosa of urinary bladder; ; nipple; ; body of pancreas;
	Top expressed in
	ganglionic eminence; ; tail of embryo; ; neural tube; ; white adipose tissue; ; Mesencephalon; ; epiblast; ; neural layer of retina; ; spermatid; ; spinal cord; ; yolk sac;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	phosphoprotein phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; hydrolase activity; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine/threonine phosphatase activity; phosphatase activity; protein tyrosine phosphatase activity; MAP kinase serine/threonine phosphatase activity; protein binding;
Cellular component	nucleoplasm; nucleus; cytoplasm;
Biological process	endoderm formation; protein dephosphorylation; peptidyl-threonine dephosphorylation; dephosphorylation; peptidyl-tyrosine dephosphorylation; negative regulation of ERK1 and ERK2 cascade;
	Sources:Amigo / QuickGO
Orthologs
	1846
	319520
	ENSG00000120875
	ENSMUSG00000031530
	Q13115
	Q8BFV3
	NM_001394; NM_057158
	NM_176933
	NP_001385; NP_476499
	NP_795907
	Wikidata
View/Edit Human	View/Edit Mouse

Dual specificity protein phosphatase 4 is an enzyme that in humans is encoded by the DUSP4 gene.