DYNC1I1

DYNC1I1
Identifiers
Aliases	DYNC1I1, dynein, cytoplasmic 1, intermediate chain 1, DNCI1, DNCIC1, dynein cytoplasmic 1 intermediate chain 1
External IDs	OMIM: 603772; MGI: 107743; HomoloGene: 68398; GeneCards: DYNC1I1; OMA:DYNC1I1 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	96,110,322 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	6,028,039 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Pons; ; pars compacta; ; middle temporal gyrus; ; frontal pole; ; superior vestibular nucleus; ; cerebellar vermis; ; pars reticulata; ; Brodmann area 23; ; lateral nuclear group of thalamus;
	Top expressed in
	pontine nuclei; ; ventral tegmental area; ; Medulla Oblongata; ; medial vestibular nucleus; ; dorsal tegmental nucleus; ; perirhinal cortex; ; deep cerebellar nuclei; ; lobe of cerebellum; ; barrel cortex; ; dorsomedial hypothalamic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	microtubule motor activity; spectrin binding; microtubule binding; protein binding; cytoskeletal motor activity; plus-end-directed microtubule motor activity; dynein light chain binding; dynein heavy chain binding;
Cellular component	cytoplasm; recycling endosome; vesicle; cytosol; spindle pole; chromosome; perinuclear region of cytoplasm; dynein complex; cytoplasmic ribonucleoprotein granule; microtubule; chromosome, centromeric region; cytoskeleton; nucleus; kinetochore; cytoplasmic dynein complex;
Biological process	antigen processing and presentation of exogenous peptide antigen via MHC class II; vesicle transport along microtubule; endoplasmic reticulum to Golgi vesicle-mediated transport; microtubule-based movement;
	Sources:Amigo / QuickGO
Orthologs
	1780
	13426
	ENSG00000158560
	ENSMUSG00000029757
	O14576
	O88485
	NM_001135556; NM_001135557; NM_001278421; NM_001278422; NM_004411
	NM_001191023; NM_001191025; NM_001191026; NM_001191027; NM_010063
	NP_001129028; NP_001129029; NP_001265350; NP_001265351; NP_004402
	NP_001177952; NP_001177954; NP_001177955; NP_001177956; NP_034193
	Wikidata
View/Edit Human	View/Edit Mouse

Cytoplasmic dynein 1 intermediate chain 1 is a protein that in humans is encoded by the DYNC1I1 gene.

In melanocytic cells DYNC1I1 gene expression may be regulated by MITF.