Derlin-2

DERL2
Identifiers
Aliases	DERL2, F-LAN-1, F-LANa, FLANa, CGI-101, DERtrin-2, derlin 2, derlin-2
External IDs	OMIM: 610304; MGI: 2151483; HomoloGene: 9356; GeneCards: DERL2; OMA:DERL2 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	5,486,811 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	70,910,667 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; body of pancreas; ; Achilles tendon; ; right lobe of liver; ; parotid gland; ; mucosa of transverse colon; ; olfactory zone of nasal mucosa; ; right adrenal gland; ; granulocyte;
	Top expressed in
	cumulus cell; ; left lobe of liver; ; seminal vesicula; ; lacrimal gland; ; decidua; ; right lung lobe; ; stroma of bone marrow; ; islet of Langerhans; ; right kidney; ; yolk sac;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; serine-type endopeptidase activity;
Cellular component	integral component of membrane; integral component of endoplasmic reticulum membrane; late endosome; early endosome; endoplasmic reticulum membrane; endoplasmic reticulum; membrane; endoplasmic reticulum quality control compartment; signal recognition particle receptor complex; signal recognition particle;
Biological process	endoplasmic reticulum unfolded protein response; positive regulation of cell growth; retrograde protein transport, ER to cytosol; response to unfolded protein; negative regulation of retrograde protein transport, ER to cytosol; positive regulation of cell population proliferation; ubiquitin-dependent ERAD pathway; suckling behavior; endoplasmic reticulum mannose trimming; proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	51009
	116891
	ENSG00000072849
	ENSMUSG00000018442
	Q9GZP9
	Q8BNI4
	NM_001304777; NM_001304779; NM_016041
	NM_001291146; NM_001291147; NM_001291148; NM_033562
	NP_001291706; NP_001291708; NP_057125
	NP_001278075; NP_001278076; NP_001278077; NP_291040
	Wikidata
View/Edit Human	View/Edit Mouse

Derlin-2 is a protein that in humans is encoded by the DERL2 gene.