Desglymidodrine

Desglymidodrine
Clinical data
Other namesDeglymidodrine; ST-1059; 3,6-Dimethoxy-β-hydroxy-2-phenylethylamine
Drug classα1-Adrenergic receptor agonist; Antihypotensive agent; Vasopressor
Identifiers
  • 2-amino-1-(2,5-dimethoxyphenyl)ethanol
CAS Number
PubChem CID
DrugBank
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.322.299
Chemical and physical data
FormulaC10H15NO3
Molar mass197.234 g·mol−1
3D model (JSmol)
  • COC1=CC(=C(C=C1)OC)C(CN)O
  • InChI=1S/C10H15NO3/c1-13-7-3-4-10(14-2)8(5-7)9(12)6-11/h3-5,9,12H,6,11H2,1-2H3
  • Key:VFRCNXKYZVQYLX-UHFFFAOYSA-N

Desglymidodrine (developmental code name ST-1059) is the active metabolite of the prodrug antihypotensive agent midodrine. It acts as a selective α1-adrenergic receptor agonist. Desglymidodrine is formed from midodrine via deglycination.