Desiccated thyroid extract

Desiccated thyroid extract
Combination of
ThyroxineThyroid hormone
TriiodothyronineThyroid hormone
Clinical data
Trade namesArmour Thyroid, NP Thyroid, Nature-Throid
Other namesNatural thyroid, natural thyroid hormones, pork thyroid, thyroid USP, thyroid BP
AHFS/Drugs.comMonograph
License data
Routes of
administration
By mouth
ATC code
  • None
Legal status
Legal status
Identifiers
CAS Number

Desiccated thyroid extract (DTE), is thyroid gland that has been dried and powdered for medical use. It is used to treat hypothyroidism, but less preferred than levothyroxine. It is taken by mouth. Maximal effects may take up to three weeks to occur.

Side effects may occur from excessive doses. This may include weight loss, fever, headache, anxiety, trouble sleeping, arrhythmias, and heart failure. Other side effects may include allergic reactions. Use in pregnancy and breastfeeding is generally safe. Regular blood tests are recommended to verify the appropriateness of the dose. They contain a mixture of thyroxine (T4) and triiodothyronine (T3).

Desiccated thyroid has been used since the late 1800s. It is usually made from pigs, sheep, or cows. It is available as a generic medication. In 2022, it was the 137th most commonly prescribed medication in the United States, with more than 4 million prescriptions. Usage has decreased since the 1960s.