Despotiko
| Native name:  Δεσποτικό | |
|---|---|
| Sanctuary of Apollo at Despotiko | |
| Geography | |
| Coordinates | 36°58′N 25°00′E / 36.96°N 25.00°E | 
| Archipelago | Cyclades | 
| Highest elevation | 187 m (614 ft) | 
| Administration | |
| Greece | |
| Region | South Aegean | 
| Regional unit | Paros | 
| Demographics | |
| Population | 0 (2001) | 
| Additional information | |
| Postal code | 840 07 | 
| Area code(s) | 22840 | 
| Vehicle registration | EM | 
Despotikó (Greek: Δεσποτικό), anciently, Prepesinthus or Prepesinthos (Ancient Greek: Πρεπέσινθος), is a small, uninhabited Greek island in the Cyclades. It is situated west of the island of Antiparos, and east of the smaller island of Strongyli (not to be confused with Strongyli Megistis).