Dimethylacetamide
| Names | |
|---|---|
| Preferred IUPAC name N,N-Dimethylacetamide | |
| Identifiers | |
| 3D model (JSmol) | |
| Abbreviations | DMA, DMAC, DMAc | 
| 1737614 | |
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.004.389 | 
| EC Number | 
 | 
| MeSH | dimethylacetamide | 
| PubChem CID | |
| RTECS number | 
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| UNII | |
| CompTox Dashboard (EPA) | |
| 
 | |
| 
 | |
| Properties | |
| C4H9NO | |
| Molar mass | 87.122 g·mol−1 | 
| Appearance | Colorless liquid | 
| Odor | Ammoniacal | 
| Density | 0.937 g/mL | 
| Melting point | −20 °C (−4 °F; 253 K) | 
| Boiling point | 165.1 °C; 329.1 °F; 438.2 K | 
| Miscible | |
| log P | −0.253 | 
| Vapor pressure | 300 Pa | 
| UV-vis (λmax) | 270 nm | 
| Refractive index (nD) | 1.4375 | 
| Viscosity | 0.945 mPa·s | 
| Thermochemistry | |
| Heat capacity (C) | 178.2 J/(K·mol) | 
| Std enthalpy of formation (ΔfH⦵298) | −300.1 kJ/mol | 
| Std enthalpy of combustion (ΔcH⦵298) | −2.5835–−2.5805 MJ/mol | 
| Hazards | |
| GHS labelling: | |
| Danger | |
| H312, H319, H332, H360 | |
| P280, P308+P313 | |
| NFPA 704 (fire diamond) | |
| Flash point | 63 °C (145 °F; 336 K) | 
| 490 °C (914 °F; 763 K) | |
| Explosive limits | 1.8–11.5% | 
| Lethal dose or concentration (LD, LC): | |
| LD50 (median dose) | 2.24 g/kg (dermal, rabbit) 4.3 g/kg (oral, rat) 4.8 g/kg (oral, rat) 4.62 g/kg (oral, mouse) | 
| LC50 (median concentration) | 2475 ppm (rat, 1 h) | 
| NIOSH (US health exposure limits): | |
| PEL (Permissible) | TWA 10 ppm (35 mg/m3) [skin] | 
| REL (Recommended) | TWA 10 ppm (35 mg/m3) [skin] | 
| IDLH (Immediate danger) | 300 ppm | 
| Related compounds | |
| Related compounds | |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references | |
Dimethylacetamide (DMAc or DMA) is the organic compound with the formula CH3C(O)N(CH3)2. This colorless, water-miscible, high-boiling liquid is commonly used as a polar solvent in organic synthesis. DMA is miscible with most other solvents, although it is poorly soluble in aliphatic hydrocarbons.