Dopamine receptor D5

DRD5
Identifiers
Aliases	DRD5, DBDR, DRD1B, DRD1L2, dopamine receptor D5
External IDs	OMIM: 126453; MGI: 94927; HomoloGene: 20216; GeneCards: DRD5; OMA:DRD5 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	9,784,009 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	38,479,861 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; tibialis anterior muscle; ; mucosa of ileum; ; prefrontal cortex; ; anterior cingulate cortex; ; deltoid muscle; ; Brodmann area 9; ; appendix; ; Hypothalamus; ; skin of thigh;
	Top expressed in
	trigeminal ganglion; ; hippocampus proper; ; spinal ganglia; ; vasculature; ; dentate gyrus of hippocampal formation granule cell; ; embryo; ; vasculature of organ; ; embryo; ; ganglion of vagus nerve; ; glossopharyngeal ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; dopamine neurotransmitter receptor activity; signal transducer activity; dopamine binding; dopamine neurotransmitter receptor activity, coupled via Gs; G-protein alpha-subunit binding;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; brush border membrane; ciliary membrane; non-motile cilium; intracellular anatomical structure; cilium;
Biological process	response to cocaine; cellular response to catecholamine stimulus; regulation of female receptivity; sensitization; adenylate cyclase-activating dopamine receptor signaling pathway; associative learning; adenylate cyclase-activating G protein-coupled receptor signaling pathway; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure; negative regulation of blood pressure; transmission of nerve impulse; response to amphetamine; regulation of systemic arterial blood pressure by vasopressin; wound healing; cellular calcium ion homeostasis; mating behavior; learning; negative regulation of NAD(P)H oxidase activity; activation of adenylate cyclase activity; reactive oxygen species metabolic process; phospholipase C-activating dopamine receptor signaling pathway; long-term depression; signal transduction; chemical synaptic transmission; synaptic transmission, dopaminergic; G protein-coupled receptor signaling pathway; positive regulation of adenylate cyclase activity;
	Sources:Amigo / QuickGO
Orthologs
	1816
	13492
	ENSG00000169676
	ENSMUSG00000039358
	P21918
	Q8BLD9
	NM_000798
	NM_013503
	NP_000789
	NP_038531
	Wikidata
View/Edit Human	View/Edit Mouse

Dopamine receptor D₅, also known as D1BR, is a protein that in humans is encoded by the DRD5 gene. It belongs to the D₁-like receptor family along with the D₁ receptor subtype.