Doxapram

Doxapram
Clinical data
Trade names	Dopram, Stimulex, Respiram
Routes of; administration	Intravenous
ATC code	R07AB01 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 1-ethyl-4- (2-morpholin-4-ylethyl)- 3,3-diphenyl-pyrrolidin-2-one;
CAS Number	309-29-5 ;
PubChem CID	3156;
DrugBank	DB00561 ;
ChemSpider	3044 ;
UNII	94F3830Q73;
KEGG	D07873 ;
ChEBI	CHEBI:681848 ;
ChEMBL	ChEMBL1754 ;
CompTox Dashboard (EPA)	DTXSID2022963 ;
ECHA InfoCard	100.005.653
Chemical and physical data
Formula	C24H30N2O2
Molar mass	378.516 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C4N(CC)CC(CCN1CCOCC1)C4(c2ccccc2)c3ccccc3;
	InChI InChI=1S/C24H30N2O2/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-12,22H,2,13-19H2,1H3 ; Key:XFDJYSQDBULQSI-UHFFFAOYSA-N ;
	(verify)

Doxapram is a respiratory stimulant, or analeptic. Administered intravenously, doxapram stimulates an increase in tidal volume, and respiratory rate.

Clinical data

Trade names	Dopram, Stimulex, Respiram
Routes of administration	Intravenous
ATC code	R07AB01 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 1-ethyl-4- (2-morpholin-4-ylethyl)- 3,3-diphenyl-pyrrolidin-2-one
CAS Number	309-29-5^Y
PubChem CID	3156
DrugBank	DB00561^Y
ChemSpider	3044^Y
UNII	94F3830Q73
KEGG	D07873^Y
ChEBI	CHEBI:681848^Y
ChEMBL	ChEMBL1754^Y
CompTox Dashboard (EPA)	DTXSID2022963
ECHA InfoCard	100.005.653
Chemical and physical data
Formula	C₂₄H₃₀N₂O₂
Molar mass	378.516 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C4N(CC)CC(CCN1CCOCC1)C4(c2ccccc2)c3ccccc3
InChI InChI=1S/C24H30N2O2/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-12,22H,2,13-19H2,1H3^Y Key:XFDJYSQDBULQSI-UHFFFAOYSA-N^Y
(verify)