Dubois Block
| Downtown Cheyenne Historic District | |
| Location | Bounded by W. Pershing Blvd., Dey Ave., W. 32nd St., and Cribbon Ave., Cheyenne, Wyoming | 
|---|---|
| Coordinates | 41°08′44″N 104°50′05″W / 41.14556°N 104.83472°W | 
| Area | less than one acre | 
| NRHP reference No. | 14000999 | 
| Added to NRHP | December 2, 2014 | 
The Dubois Block was listed on the National Register of Historic Places in 2014. The listing included 11 contributing buildings and three non-contributing ones.
It includes six houses designed by Cheyenne architect William R. Dubois.