E2F4

E2F4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1CF7
Identifiers
Aliases	E2F4, E2F-4, E2F transcription factor 4
External IDs	OMIM: 600659; MGI: 103012; HomoloGene: 1471; GeneCards: E2F4; OMA:E2F4 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	67,198,918 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	106,032,002 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; granulocyte; ; left uterine tube; ; anterior pituitary; ; transverse colon; ; mucosa of transverse colon; ; apex of heart; ; body of stomach; ; right lobe of thyroid gland; ; upper lobe of left lung;
	Top expressed in
	tail of embryo; ; zygote; ; yolk sac; ; genital tubercle; ; ventricular zone; ; embryo; ; neural layer of retina; ; lip; ; muscle of thigh; ; granulocyte;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein domain specific binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; transcription factor binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; promoter-specific chromatin binding; protein dimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; sequence-specific DNA binding;
Cellular component	transcription regulator complex; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex;
Biological process	regulation of cell size; epithelial cell development; cell volume homeostasis; regulation of transcription, DNA-templated; multi-ciliated epithelial cell differentiation; transcription by RNA polymerase II; regulation of transcription involved in G1/S transition of mitotic cell cycle; blood circulation; cell projection organization; regulation of cell population proliferation; animal organ morphogenesis; cell cycle; motile cilium assembly; centriole assembly; transcription, DNA-templated; mitotic cell cycle; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; positive regulation of transcription by RNA polymerase II; cilium assembly; negative regulation of transcription by RNA polymerase II; regulation of cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	1874
	104394
	ENSG00000205250
	ENSMUSG00000014859
	Q16254
	Q8R0K9
	NM_001950
	NM_148952
	NP_001941
	NP_683754
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor E2F4 is a protein that in humans is encoded by the E2F4 gene.