EAF2

EAF2
Identifiers
Aliases	EAF2, BM040, TRAITS, U19, ELL associated factor 2
External IDs	OMIM: 607659; MGI: 2146616; HomoloGene: 10208; GeneCards: EAF2; OMA:EAF2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	121,886,526 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	36,695,365 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; monocyte; ; lymph node; ; trabecular bone; ; granulocyte; ; appendix; ; kidney tubule; ; epithelium of nasopharynx; ; rectum; ; spleen;
	Top expressed in
	female urethra; ; right kidney; ; proximal tubule; ; lacrimal gland; ; epithelium of urethra; ; epithelium of female urethra; ; seminal vesicula; ; pelvic part of vagina; ; male urethra; ; epithelium of male urethra;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein binding;
Cellular component	nuclear speck; transcription elongation factor complex; super elongation complex; nucleus; nucleoplasm;
Biological process	positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; negative regulation of cell growth; negative regulation of epithelial cell proliferation involved in prostate gland development; positive regulation of transcription by RNA polymerase II; transcription, DNA-templated; apoptotic process; transcription by RNA polymerase II; transcription elongation from RNA polymerase II promoter;
	Sources:Amigo / QuickGO
Orthologs
	55840
	106389
	ENSG00000145088
	ENSMUSG00000022838
	Q96CJ1
	Q91ZD6
	NM_018456; NM_001320041
	NM_001113401; NM_001113405; NM_134111; NM_001358102
	NP_001306970; NP_060926
	NP_001106872; NP_001106876; NP_598872; NP_001345031
	Wikidata
View/Edit Human	View/Edit Mouse

ELL-associated factor 2 is a protein that in humans is encoded by the EAF2 gene. It is part of the EAF family of proteins and plays a role in transcriptional elongation by interacting with ELL proteins.