EBAG9

EBAG9
Identifiers
Aliases	EBAG9, EB9, PDAF, estrogen receptor binding site associated, antigen, 9, estrogen receptor binding site associated antigen 9
External IDs	OMIM: 605772; MGI: 1859920; HomoloGene: 3107; GeneCards: EBAG9; OMA:EBAG9 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	109,565,996 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	44,504,911 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; corpus epididymis; ; caput epididymis; ; endothelial cell; ; Achilles tendon; ; kidney tubule; ; tail of epididymis; ; Brodmann area 23; ; Epithelium of choroid plexus; ; glomerulus;
	Top expressed in
	seminal vesicula; ; parotid gland; ; submandibular gland; ; atrioventricular valve; ; tail of embryo; ; triceps brachii muscle; ; endocardial cushion; ; genital tubercle; ; migratory enteric neural crest cell; ; ascending aorta;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	peptidase activator activity involved in apoptotic process;
Cellular component	integral component of membrane; Golgi apparatus; secretory granule; membrane; Golgi membrane;
Biological process	regulation of cell growth; apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	9166
	55960
	ENSG00000147654
	ENSMUSG00000022339
	O00559
	Q9D0V7
	NM_198120; NM_001278938; NM_004215
	NM_019480; NM_001357690; NM_001357691
	NP_001265867; NP_004206; NP_936056
	NP_062353; NP_001344619; NP_001344620
	Wikidata
View/Edit Human	View/Edit Mouse

Receptor-binding cancer antigen expressed on SiSo cells is a protein that in humans is encoded by the EBAG9 gene.

This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.