ECT2

ECT2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3L46, 4N40
Identifiers
Aliases	ECT2, ARHGEF31, epithelial cell transforming 2
External IDs	OMIM: 600586; MGI: 95281; HomoloGene: 7298; GeneCards: ECT2; OMA:ECT2 - orthologs
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	27,208,027 bp
RNA expression pattern
	n/a
	Top expressed in
	medial ganglionic eminence; ; zygote; ; secondary oocyte; ; primary oocyte; ; ventricular zone; ; tail of embryo; ; cumulus cell; ; genital tubercle; ; abdominal wall; ; Gonadal ridge;
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; GTPase activator activity; signal transducer activity; protein binding; guanyl-nucleotide exchange factor activity;
Cellular component	cytoplasm; centralspindlin complex; cell-cell junction; bicellular tight junction; spindle; cell junction; midbody; cleavage furrow; mitotic spindle; cytoskeleton; nucleus; cytosol;
Biological process	cellular response to calcium ion; cell differentiation; intracellular signal transduction; activation of GTPase activity; nervous system development; cell division; positive regulation of cytokinesis; positive regulation of GTPase activity; positive regulation of neuron differentiation; bicellular tight junction assembly; cell morphogenesis; positive regulation of apoptotic process; cellular response to ionizing radiation; protein transport; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of protein import into nucleus; cell cycle; regulation of protein kinase activity; regulation of Rho protein signal transduction; regulation of attachment of spindle microtubules to kinetochore; regulation of small GTPase mediated signal transduction; protein homooligomerization; activation of protein kinase activity; cellular response to hydrogen peroxide; transport; mitotic cytokinesis; cytokinesis; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	1894
	13605
	ENSG00000114346
	ENSMUSG00000027699
	Q9H8V3
	Q07139
	NM_001258315; NM_001258316; NM_018098
	NM_001177625; NM_001177626; NM_007900
NP_001245244; NP_001245245; NP_060568; NP_001336023; NP_001336024;
	NP_001336025; NP_001336026; NP_001336027; NP_001336028; NP_001336029; NP_001336030; NP_001336031; NP_001336032; NP_001336033
	NP_001171096; NP_001171097; NP_031926
	Wikidata
View/Edit Human	View/Edit Mouse

Protein ECT2 is a protein that in humans is encoded by the ECT2 gene.