EDEM3

EDEM3
Identifiers
Aliases	EDEM3, C1orf22, ER degradation enhancing alpha-mannosidase like protein 3, CDG2V
External IDs	OMIM: 610214; MGI: 1914217; HomoloGene: 11866; GeneCards: EDEM3; OMA:EDEM3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	184,754,907 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	151,697,802 bp
RNA expression pattern
	Top expressed in
	pylorus; ; mucosa of sigmoid colon; ; jejunal mucosa; ; mucosa of paranasal sinus; ; trabecular bone; ; islet of Langerhans; ; stromal cell of endometrium; ; cardia; ; body of pancreas; ; rectum;
	Top expressed in
	lacrimal gland; ; seminal vesicula; ; salivary gland; ; parotid gland; ; submandibular gland; ; cumulus cell; ; left lung lobe; ; pineal gland; ; epithelium of stomach; ; crypt of lieberkuhn of small intestine;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; hydrolase activity; metal ion binding; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; catalytic activity;
Cellular component	endoplasmic reticulum lumen; endoplasmic reticulum; membrane; endoplasmic reticulum quality control compartment;
Biological process	endoplasmic reticulum unfolded protein response; protein glycosylation; N-glycan processing; response to unfolded protein; glycoprotein catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process; mannose trimming involved in glycoprotein ERAD pathway;
	Sources:Amigo / QuickGO
Orthologs
	80267
	66967
	ENSG00000116406
	ENSMUSG00000043019
	Q9BZQ6
	Q2HXL6
	NM_025191; NM_001319960
	NM_001039644; NM_001311165; NM_001311166
	NP_001306889; NP_079467
	NP_001034733; NP_001298094; NP_001298095
	Wikidata
View/Edit Human	View/Edit Mouse

ER degradation-enhancing alpha-mannosidase-like 3 is an enzyme that in humans is encoded by the EDEM3 gene.