EEF2K

EEF2K
Identifiers
Aliases	EEF2K, HSU93850, eEF-2K, eukaryotic elongation factor 2 kinase, CAMKIII, calmodulin-dependent protein kinase III
External IDs	OMIM: 606968; MGI: 1195261; HomoloGene: 7299; GeneCards: EEF2K; OMA:EEF2K - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	22,288,738 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	120,506,673 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; sural nerve; ; skin of abdomen; ; muscle of thigh; ; Cerebellum; ; cerebellar cortex; ; cerebellar hemisphere; ; skeletal muscle tissue; ; right hemisphere of cerebellum; ; gastric mucosa;
	Top expressed in
	ascending aorta; ; primary oocyte; ; aortic valve; ; secondary oocyte; ; zygote; ; seminal vesicula; ; urothelium; ; urinary bladder; ; transitional epithelium of urinary bladder; ; medullary collecting duct;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; calcium ion binding; protein kinase activity; transferase activity; protein serine/threonine kinase activity; kinase activity; translation factor activity, RNA binding; calmodulin binding; ATP binding; elongation factor-2 kinase activity;
Cellular component	cytoplasm; cytosol; postsynaptic density; dendritic spine;
Biological process	positive regulation of endocytosis; cellular response to cAMP; response to ischemia; negative regulation of apoptotic process; cellular response to insulin stimulus; positive regulation of synapse assembly; translational elongation; cellular response to calcium ion; protein autophosphorylation; cellular response to brain-derived neurotrophic factor stimulus; cellular response to anoxia; protein phosphorylation; positive regulation of dendritic spine morphogenesis; regulation of protein autophosphorylation; response to prolactin; phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	29904
	13631
	ENSG00000103319; ENSG00000284161
	ENSMUSG00000035064
	O00418
	O08796
	NM_013302
	NM_001267710; NM_001267711; NM_007908
	NP_037434
	NP_001254639; NP_001254640; NP_031934
	Wikidata
View/Edit Human	View/Edit Mouse

Eukaryotic elongation factor-2 kinase (eEF-2 kinase or eEF-2K), also known as calmodulin-dependent protein kinase III (CAMKIII) and calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, is an enzyme that in humans is encoded by the EEF2K gene.