EF-Ts
| EF-Ts, bacterial | |
|---|---|
| Identifiers | |
| Symbol | EF-Ts/EF-1B |
| InterPro | IPR001816 |
| EF-Ts dimerisation domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | EF_TS | ||||||||
| Pfam | PF00889 | ||||||||
| InterPro | IPR014039 | ||||||||
| |||||||||
EF-Ts (elongation factor thermo stable) is one of the prokaryotic elongation factors. It is found in human mitochondria as TSFM. It is similar to eukaryotic EF-1B.
EF-Ts serves as the guanine nucleotide exchange factor for EF-Tu (elongation factor thermo unstable), catalyzing the release of guanosine diphosphate from EF-Tu. This enables EF-Tu to bind to a new guanosine triphosphate molecule, release EF-Ts, and go on to catalyze another aminoacyl tRNA addition.