EFTUD2

EFTUD2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3JCR
Identifiers
Aliases	EFTUD2, MFDGA, MFDM, SNRNP116, Snrp116, Snu114, U5-116KD, elongation factor Tu GTP binding domain containing 2
External IDs	OMIM: 603892; MGI: 1336880; HomoloGene: 3133; GeneCards: EFTUD2; OMA:EFTUD2 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	44,899,445 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	102,771,811 bp
RNA expression pattern
	Top expressed in
	bone marrow cells; ; tibialis anterior muscle; ; ventricular zone; ; monocyte; ; mucosa of ileum; ; ganglionic eminence; ; skin of arm; ; gastrocnemius muscle; ; stromal cell of endometrium; ; islet of Langerhans;
	Top expressed in
	maxillary prominence; ; mandibular prominence; ; tail of embryo; ; abdominal wall; ; somite; ; dermis; ; epiblast; ; internal carotid artery; ; external carotid artery; ; primitive streak;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity; RNA binding; U5 snRNA binding;
Cellular component	Cajal body; nuclear speck; catalytic step 2 spliceosome; spliceosomal complex; membrane; nucleus; nucleoplasm; extracellular matrix; cytosol; U4/U6 x U5 tri-snRNP complex; U2-type catalytic step 2 spliceosome; ribonucleoprotein complex; U2-type precatalytic spliceosome;
Biological process	mRNA splicing, via spliceosome; mRNA processing; RNA splicing; response to cocaine;
	Sources:Amigo / QuickGO
Orthologs
	9343
	20624
	ENSG00000108883
	ENSMUSG00000020929
	Q15029
	O08810
	NM_001142605; NM_001258353; NM_001258354; NM_004247
	NM_001109995; NM_011431
	NP_001136077; NP_001245282; NP_001245283; NP_004238
	NP_001103465; NP_035561
	Wikidata
View/Edit Human	View/Edit Mouse

116 kDa U5 small nuclear ribonucleoprotein component is a protein that in humans is encoded by the EFTUD2 gene.