EHF (gene)

EHF
Identifiers
Aliases	EHF, ESE3, ESE3B, ESEJ, ETS homologous factor
External IDs	OMIM: 605439; MGI: 1270840; HomoloGene: 7301; GeneCards: EHF; OMA:EHF - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	34,661,057 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	103,133,623 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; gingival epithelium; ; seminal vesicula; ; oral cavity; ; bronchial epithelial cell; ; mucosa of sigmoid colon; ; epithelium of nasopharynx; ; skin of thigh; ; vulva; ; mucosa of pharynx;
	Top expressed in
	lacrimal gland; ; submandibular gland; ; parotid gland; ; prostate; ; lobe of prostate; ; left colon; ; mucosa of urinary bladder; ; transitional epithelium of urinary bladder; ; conjunctival fornix; ; seminal vesicula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	Golgi apparatus; nucleoplasm; nucleus;
Biological process	multicellular organism development; positive regulation of transcription, DNA-templated; cell population proliferation; epithelial cell proliferation; regulation of transcription, DNA-templated; epithelial cell differentiation; transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	26298
	13661
	ENSG00000135373
	ENSMUSG00000012350
	Q9NZC4
	O70273
	NM_001206615; NM_001206616; NM_012153
	NM_007914
NP_001193544; NP_001193545; NP_036285; NP_001364970; NP_001364971;
	NP_001364972; NP_001364973; NP_001364974; NP_001364975; NP_001364976; NP_001364977; NP_001364978; NP_001364979; NP_001364980; NP_001364981; NP_001364982; NP_001364983; NP_001364984; NP_001364985
	NP_031940
	Wikidata
View/Edit Human	View/Edit Mouse

ETS homologous factor is a protein that in humans is encoded by the EHF gene. This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be associated with asthma susceptibility. This protein may be involved in epithelial differentiation and carcinogenesis.