LGTN

EIF2D
Identifiers
Aliases	EIF2D, HCA56, LGTN, eukaryotic translation initiation factor 2D
External IDs	OMIM: 613709; MGI: 109342; HomoloGene: 38244; GeneCards: EIF2D; OMA:EIF2D - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	206,612,465 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	131,115,395 bp
RNA expression pattern
	Top expressed in
	left ovary; ; body of uterus; ; right ovary; ; right uterine tube; ; glutes; ; muscle of thigh; ; parotid gland; ; body of pancreas; ; muscle layer of sigmoid colon; ; canal of the cervix;
	Top expressed in
	Paneth cell; ; fossa; ; condyle; ; hair follicle; ; internal carotid artery; ; lacrimal gland; ; primitive streak; ; external carotid artery; ; endothelial cell of lymphatic vessel; ; epiblast;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	translation initiation factor activity; RNA binding; signaling receptor activity;
Cellular component	cytoplasm; cytosolic small ribosomal subunit; cytosol; nuclear body;
Biological process	translational initiation; intracellular protein transport; ribosome disassembly; protein biosynthesis; formation of translation preinitiation complex; IRES-dependent viral translational initiation; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	1939
	16865
	ENSG00000143486
	ENSMUSG00000026427
	P41214; Q5SY38
	Q61211
	NM_001201478; NM_006893
	NM_001136070; NM_010709
	NP_001188407; NP_008824
	NP_001129542; NP_034839
	Wikidata
View/Edit Human	View/Edit Mouse

Ligatin, otherwise known as eIF2D, is a protein that in humans is encoded by the LGTN gene. This protein is not a component of the heterotrimeric eIF2 complex, but instead functions in different pathways of eukaryotic translation.