ELAC2

ELAC2
Identifiers
Aliases	ELAC2, COXPD17, ELC2, HPC2, elaC ribonuclease Z 2
External IDs	OMIM: 605367; MGI: 1890496; HomoloGene: 6403; GeneCards: ELAC2; OMA:ELAC2 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	13,018,065 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	64,892,895 bp
RNA expression pattern
	Top expressed in
	gastric mucosa; ; apex of heart; ; right adrenal cortex; ; left adrenal gland; ; sural nerve; ; left adrenal cortex; ; gastrocnemius muscle; ; epithelium of colon; ; left ventricle; ; islet of Langerhans;
	Top expressed in
	otic placode; ; saccule; ; otic vesicle; ; perirhinal cortex; ; entorhinal cortex; ; spermatocyte; ; epiblast; ; zygote; ; yolk sac; ; CA3 field;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	endonuclease activity; nuclease activity; hydrolase activity; metal ion binding; tRNA-specific ribonuclease activity; RNA binding; 3'-tRNA processing endoribonuclease activity;
Cellular component	mitochondrial matrix; mitochondrial nucleoid; mitochondrion; nucleus; nucleoplasm;
Biological process	mitochondrial tRNA 3'-trailer cleavage, endonucleolytic; mitochondrial tRNA processing; tRNA 3'-end processing; tRNA processing;
	Sources:Amigo / QuickGO
Orthologs
	60528
	68626
	ENSG00000006744
	ENSMUSG00000020549
	Q9BQ52
	Q80Y81
	NM_173717; NM_001165962; NM_018127
	NM_023479; NM_001362982; NM_001362983; NM_001362984
	NP_001159434; NP_060597; NP_776065
	NP_075968; NP_001349911; NP_001349912; NP_001349913
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc phosphodiesterase ELAC protein 2 is an enzyme that in humans is encoded by the ELAC2 gene. on chromosome 17. It is an endonuclease thought to be involved in mitochondrial tRNA maturation,