ELMO1

ELMO1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2RQR, 2VSZ, 3A98
Identifiers
Aliases	ELMO1, CED-12, CED12, ELMO-1, engulfment and cell motility 1
External IDs	OMIM: 606420; MGI: 2153044; HomoloGene: 56685; GeneCards: ELMO1; OMA:ELMO1 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	37,449,223 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	20,792,523 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; C1 segment; ; corpus callosum; ; Brodmann area 9; ; sural nerve; ; right frontal lobe; ; islet of Langerhans; ; lateral nuclear group of thalamus; ; postcentral gyrus; ; ganglionic eminence;
	Top expressed in
	medial dorsal nucleus; ; medial geniculate nucleus; ; lateral geniculate nucleus; ; pallidum of neuraxis; ; globus pallidus; ; pontine nuclei; ; deep cerebellar nuclei; ; inferior colliculi; ; granulocyte; ; cerebellar cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	guanyl-nucleotide exchange factor activity; SH3 domain binding; protein binding;
Cellular component	cytosol; cytoplasm; guanyl-nucleotide exchange factor complex; plasma membrane; membrane;
Biological process	Fc-gamma receptor signaling pathway involved in phagocytosis; actin filament-based process; mitigation of host defenses by virus; phagocytosis, engulfment; vascular endothelial growth factor receptor signaling pathway; phagocytosis; Rac protein signal transduction; cell migration; actin cytoskeleton organization; apoptotic process; cell motility; regulation of molecular function;
	Sources:Amigo / QuickGO
Orthologs
	9844
	140580
	ENSG00000155849
	ENSMUSG00000041112
	Q92556
	Q8BPU7
	NM_001039459; NM_001206480; NM_001206482; NM_014800; NM_130442
	NM_080288; NM_198093
	NP_001034548; NP_001193409; NP_001193411; NP_055615; NP_569709
	NP_525027; NP_932761
	Wikidata
View/Edit Human	View/Edit Mouse

Engulfment and cell motility protein 1 is a protein that in humans is encoded by the ELMO1 gene. ELMO1 is located on chromosome number seven in humans and is located on chromosome number thirteen in mice.