EMG1

EMG1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5FAI
Identifiers
Aliases	EMG1, C2F, Grcc2f, NEP1, N1-specific pseudouridine methyltransferase, EMG1 N1-specific pseudouridine methyltransferase
External IDs	OMIM: 611531; MGI: 1315195; HomoloGene: 4617; GeneCards: EMG1; OMA:EMG1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	124,689,141 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; stromal cell of endometrium; ; left ventricle; ; right adrenal gland; ; right lobe of thyroid gland; ; appendix; ; left uterine tube; ; left lobe of thyroid gland; ; oocyte; ; left adrenal gland;
	Top expressed in
	medial ganglionic eminence; ; mandibular prominence; ; maxillary prominence; ; somite; ; endocardial cushion; ; thymus; ; fetal liver hematopoietic progenitor cell; ; abdominal wall; ; epiblast; ; migratory enteric neural crest cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; rRNA binding; protein binding; rRNA (pseudouridine) methyltransferase activity; RNA binding;
Cellular component	cytoplasm; small-subunit processome; nucleoplasm; nucleus; nucleolus;
Biological process	rRNA base methylation; methylation; ribosomal small subunit biogenesis; ribosome biogenesis; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); rRNA processing; blastocyst development; nucleologenesis;
	Sources:Amigo / QuickGO
Orthologs
	10436
	14791
	n/a
	ENSMUSG00000004268
	Q92979
	O35130
	NM_006331; NM_001320049
	NM_013536
	NP_001306978; NP_006322
	NP_038564
	Wikidata
View/Edit Human	View/Edit Mouse

Probable ribosome biogenesis protein NEP1 or EMG1 is a protein that in humans is encoded by the EMG1 gene. A D86G mutation in the protein has been associated with Bowen-Conradi syndrome.