EMP3

EMP3
Identifiers
Aliases	EMP3, YMP, epithelial membrane protein 3
External IDs	OMIM: 602335; MGI: 1098729; HomoloGene: 1090; GeneCards: EMP3; OMA:EMP3 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	48,330,553 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	45,570,828 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; synovial joint; ; stromal cell of endometrium; ; smooth muscle tissue; ; canal of the cervix; ; synovial membrane; ; body of uterus; ; right lung; ; left uterine tube;
	Top expressed in
	calvaria; ; granulocyte; ; adrenal gland; ; ankle; ; external carotid artery; ; internal carotid artery; ; lip; ; umbilical cord; ; facial skeleton; ; efferent ductule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	bleb assembly; cell death; negative regulation of cell population proliferation; cell growth;
	Sources:Amigo / QuickGO
Orthologs
	2014
	13732
	ENSG00000142227
	ENSMUSG00000040212
	P54852
	O35912
	NM_001313905; NM_001425
	NM_001146346; NM_010129
	NP_001300834; NP_001416
	NP_001139818; NP_034259
	Wikidata
View/Edit Human	View/Edit Mouse

Epithelial membrane protein 3 (EMP3) is a trans-membrane signaling molecule that is encoded by the myelin-related gene EMP3. EMP3 is a member of the peripheral myelin protein gene family 22-kDa (PMP22), which is mainly responsible for the formation of the sheath of compact myelin. Although the detailed functions and mechanisms of EMP3 still remain unclear, it is suggested that EMP3 is possibly epigenetically linked to certain carcinomas.