EMX1

EMX1
Identifiers
Aliases	EMX1, empty spiracles homeobox 1
External IDs	OMIM: 600034; MGI: 95387; HomoloGene: 55799; GeneCards: EMX1; OMA:EMX1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	72,936,071 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	85,181,444 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; oocyte; ; gonad; ; right frontal lobe; ; human kidney; ; Brodmann area 9; ; prefrontal cortex; ; cingulate gyrus; ; anterior cingulate cortex;
	Top expressed in
	ventricular zone; ; Subplate; ; primary visual cortex; ; right kidney; ; superior frontal gyrus; ; otic vesicle; ; dentate gyrus of hippocampal formation granule cell; ; renal cortex; ; human kidney; ; proximal tubule;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	sequence-specific DNA binding; DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; nucleus; nucleolus;
Biological process	regulation of transcription, DNA-templated; homeostasis of number of cells; cerebral cortex regionalization; in utero embryonic development; post-embryonic development; neuron projection extension; neuroepithelial cell differentiation; radial glial cell differentiation; multicellular organism development; regulation of oligodendrocyte progenitor proliferation; telencephalon development; brain development; neuron differentiation; cerebral cortex development; cerebral cortex neuron differentiation; brain morphogenesis; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	2016
	13796
	ENSG00000135638
	ENSMUSG00000033726
	Q04741
	Q04742
	NM_001040404; NM_004097
	NM_010131
	NP_004088
	NP_034261
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein EMX1 is a protein that in humans is encoded by the EMX1 gene. The transcribed EMX1 gene is a member of the EMX family of transcription factors. The EMX1 gene, along with its family members, are expressed in the developing cerebrum (also known as the telencephalon). EMX1 plays a role in specification of positional identity, the proliferation of neural stem cells, differentiation of layer-specific neuronal phenotypes and commitment to a neuronal or glial cell fate.