ENPP7

ENPP7
Identifiers
Aliases	ENPP7, ALK-SMase, E-NPP 7, NPP-7, NPP7, ectonucleotide pyrophosphatase/phosphodiesterase 7
External IDs	OMIM: 616997; MGI: 3027917; HomoloGene: 110852; GeneCards: ENPP7; OMA:ENPP7 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	79,742,219 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	118,884,047 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; duodenum; ; tendon of biceps brachii; ; testicle; ; vena cava; ; liver; ; Skeletal muscle tissue of rectus abdominis; ; right lobe of liver; ; trabecular bone; ; cerebellar vermis;
	Top expressed in
	jejunum; ; placenta; ; ileum; ; yolk sac; ; blastocyst; ; duodenum; ; colon; ; stomach;
	More reference expression data
	n/a
Gene ontology
Molecular function	catalytic activity; hydrolase activity; sphingomyelin phosphodiesterase activity; zinc ion binding; metal ion binding;
Cellular component	integral component of membrane; microvillus; plasma membrane; Golgi apparatus; membrane; integral component of plasma membrane;
Biological process	metabolism; sphingomyelin catabolic process; negative regulation of DNA replication; glycosphingolipid metabolic process; negative regulation of cell population proliferation; sphingomyelin metabolic process; lipid metabolism;
	Sources:Amigo / QuickGO
Orthologs
	339221
	238011
	ENSG00000182156
	ENSMUSG00000046697
	Q6UWV6
	n/a
	NM_178543
	NM_001030291; NM_001359574
	NP_848638
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) also known as alkaline sphingomyelin phosphodiesterase (Alk-SMase) or intestinal alkaline sphingomyelinase is an enzyme that in humans is encoded by the ENPP7 gene.