EPH receptor B2

EPHB2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1B4F, 1F0M, 2QBX, 3ZFM
Identifiers
Aliases	EPHB2, Ephb2, Cek5, Drt, ETECK, Erk, Hek5, Nuk, Prkm5, Qek5, Sek3, Tyro5, CAPB, EK5, EPHT3, PCBC, EPH receptor B2, DRT, ERK, BDPLT22
External IDs	OMIM: 600997; MGI: 99611; HomoloGene: 37925; GeneCards: EPHB2; OMA:EPHB2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	22,921,500 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	136,563,299 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; rectum; ; mucosa of transverse colon; ; cartilage tissue; ; mucosa of sigmoid colon; ; buccal mucosa cell; ; tendon of biceps brachii; ; duodenum; ; islet of Langerhans;
	Top expressed in
	Rostral migratory stream; ; internal carotid artery; ; crypt of lieberkuhn of small intestine; ; tail of embryo; ; ventricular zone; ; genital tubercle; ; external carotid artery; ; Paneth cell; ; ganglionic eminence; ; efferent ductule;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; transmembrane-ephrin receptor activity; kinase activity; protein binding; identical protein binding; transmembrane receptor protein tyrosine kinase activity; protein tyrosine kinase activity; signaling receptor binding; ATP binding; axon guidance receptor activity; ephrin receptor activity; amyloid-beta binding; signaling receptor activity; protein-containing complex binding;
Cellular component	integral component of membrane; cytosol; cell projection; membrane; integral component of plasma membrane; extracellular region; axon; soma; dendrite; nucleus; plasma membrane; neuron projection; receptor complex; postsynapse; glutamatergic synapse; integral component of postsynaptic membrane; integral component of presynaptic membrane;
Biological process	positive regulation of synapse assembly; roof of mouth development; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; optic nerve morphogenesis; ephrin receptor signaling pathway; learning; commissural neuron axon guidance; nervous system development; multicellular organism development; regulation of axonogenesis; dendritic spine development; dendritic spine morphogenesis; negative regulation of axonogenesis; protein phosphorylation; positive regulation of long-term neuronal synaptic plasticity; regulation of body fluid levels; inner ear morphogenesis; angiogenesis; cell morphogenesis; animal organ morphogenesis; regulation of neuronal synaptic plasticity; urogenital system development; peptidyl-tyrosine phosphorylation; corpus callosum development; central nervous system projection neuron axonogenesis; axonal fasciculation; camera-type eye morphogenesis; retinal ganglion cell axon guidance; axon guidance; trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission; negative regulation of protein phosphorylation; learning or memory; positive regulation of gene expression; positive regulation of synaptic plasticity; negative regulation of Ras protein signal transduction; regulation of synapse assembly; negative regulation of ERK1 and ERK2 cascade; postsynaptic membrane assembly; neuron projection retraction; positive regulation of long-term synaptic potentiation; positive regulation of protein localization to plasma membrane; negative regulation of NMDA glutamate receptor activity; positive regulation of NMDA glutamate receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	2048
	13844
	ENSG00000133216
	ENSMUSG00000028664
	P29323
	P54763
	NM_001309192; NM_001309193; NM_004442; NM_017449
	NM_001290753; NM_010142
	NP_001296121; NP_001296122; NP_004433; NP_059145
	NP_001277682; NP_034272
	Wikidata
View/Edit Human	View/Edit Mouse

Ephrin type-B receptor 2 is a protein that in humans is encoded by the EPHB2 gene.