EPHB3

EPHB3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3P1I, 3ZFY
Identifiers
Aliases	EPHB3, ETK2, HEK2, TYRO6, EPH receptor B3, EK2
External IDs	OMIM: 601839; MGI: 104770; HomoloGene: 20938; GeneCards: EPHB3; OMA:EPHB3 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	184,582,408 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	21,042,055 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; skin of leg; ; skin of abdomen; ; gingival epithelium; ; parotid gland; ; mucosa of transverse colon; ; periodontal fiber; ; skin of arm; ; hair follicle; ; rectum;
	Top expressed in
	saccule; ; otic placode; ; otic vesicle; ; lip; ; tongue; ; corneal stroma; ; molar; ; skin of abdomen; ; esophagus; ; calvaria;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; transmembrane receptor protein tyrosine kinase activity; protein kinase activity; kinase activity; ATP binding; transferase activity; ephrin receptor activity; axon guidance receptor activity; protein tyrosine kinase activity; receptor tyrosine kinase; transmembrane signaling receptor activity; transmembrane-ephrin receptor activity;
Cellular component	extracellular region; dendrite; integral component of membrane; cell projection; membrane; cytosol; plasma membrane; integral component of plasma membrane; cytoplasm; neuron projection; receptor complex;
Biological process	phosphorylation; peptidyl-tyrosine phosphorylation; nervous system development; multicellular organism development; regulation of cell-cell adhesion; protein phosphorylation; substrate adhesion-dependent cell spreading; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of GTPase activity; protein autophosphorylation; angiogenesis; ephrin receptor signaling pathway; urogenital system development; axon guidance; axonal fasciculation; cell migration; central nervous system projection neuron axonogenesis; corpus callosum development; retinal ganglion cell axon guidance; thymus development; digestive tract morphogenesis; regulation of axonogenesis; positive regulation of synapse assembly; roof of mouth development; dendritic spine development; dendritic spine morphogenesis; negative regulation of signal transduction; cell differentiation; negative regulation of apoptotic process; positive regulation of ERK1 and ERK2 cascade;
	Sources:Amigo / QuickGO
Orthologs
	2049
	13845
	ENSG00000182580
	ENSMUSG00000005958
	P54753
	P54754
	NM_004443
	NM_010143
	NP_004434
	NP_034273
	Wikidata
View/Edit Human	View/Edit Mouse

Ephrin type-B receptor 3 is a protein that in humans is encoded by the EPHB3 gene.