ERB-196

ERB-196
Clinical data
Other names	WAY-202196
Identifiers
	IUPAC name 3-(3-Fluoro-4-hydroxyphenyl)-7-hydroxynaphthalene-1-carbonitrile;
CAS Number	550997-55-2;
PubChem CID	6102691;
DrugBank	DB06875;
ChemSpider	4810213;
UNII	470CL5L4AC;
ChEMBL	ChEMBL192154;
CompTox Dashboard (EPA)	DTXSID70422018 ;
Chemical and physical data
Formula	C17H10FNO2
Molar mass	279.270 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1(=CC2=C(C(=C1)C#N)C=C(C=C2)O)C1=CC(=C(C=C1)O)F;
	InChI InChI=1S/C17H10FNO2/c18-16-7-10(2-4-17(16)21)12-5-11-1-3-14(20)8-15(11)13(6-12)9-19/h1-8,20-21H; Key:NSSOSHDCWCMNDM-UHFFFAOYSA-N;

ERB-196, also known as WAY-202196, is a synthetic nonsteroidal estrogen that acts as a highly selective agonist of the ERβ. It possesses 78-fold selectivity for the ERβ over the ERα. The drug was under development by Wyeth for the treatment of inflammation and sepsis starting in 2004 but development was discontinued by 2011.